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Therapeutic Efficacy and Safety of Paclitaxel/Lonidamine Loaded EGFR-Targeted Nanoparticles for the Treatment of Multi-Drug Resistant Cancer

The treatment of multi-drug resistant (MDR) cancer is a clinical challenge. Many MDR cells over-express epidermal growth factor receptor (EGFR). We exploit this expression through the development of EGFR-targeted, polymer blend nanocarriers for the treatment of MDR cancer using paclitaxel (a common...

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Detalhes bibliográficos
Main Authors: Milane, Lara, Duan, Zhenfeng, Amiji, Mansoor
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169576/
https://ncbi.nlm.nih.gov/pubmed/21931642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024075
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