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Development of EGFR-Targeted Polymer Blend Nanocarriers for Combination Paclitaxel/Lonidamine Delivery to Treat Multi-Drug Resistance in Human Breast and Ovarian Tumor Cells

Multi-drug resistant (MDR) cancer is a significant clinical obstacle and is often implicated in cases of recurrent, non-responsive disease. Targeted nanoparticles were made by synthesizing a poly(D,L-lactide-co-glycolide)/poly(ethylene glycol)/epidermal growth factor receptor targeting peptide (PLGA...

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Detalhes bibliográficos
Main Authors: Milane, Lara, Duan, Zhenfeng, Amiji, Mansoor
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817847/
https://ncbi.nlm.nih.gov/pubmed/20942457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp1002653
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