Biodistribution and Pharmacokinetic Analysis of Paclitaxel and Ceramide Administered in Multifunctional Polymer-Blend Nanoparticles in Drug Resistant Breast Cancer Model

[Image: see text] In this study, we have investigated the biodistribution and pharmacokinetic analysis of paclitaxel (PTX) and the apoptotic signaling molecule, C(6)-ceramide (CER), when administered in a multifunctional polymer-blend nanoparticle formulation to female nude mice bearing an orthotopi...

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Hauptverfasser: van Vlerken, Lilian E., Duan, Zhenfeng, Little, Steven R., Seiden, Michael V., Amiji, Mansoor M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2008
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646668/
https://ncbi.nlm.nih.gov/pubmed/18616278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp800030k
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