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Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation

The mechanisms that control cell proliferation and cell differentiation during morphogenesis of the endochondral skeleton of vertebrates are poorly understood. Indian hedgehog (Ihh) signaling from prehypertrophic chondrocytes has been implicated in the control of chondrocyte maturation by way of fee...

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Auteurs principaux: St-Jacques, Benoit, Hammerschmidt, Matthias, McMahon, Andrew P.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC316949/
https://ncbi.nlm.nih.gov/pubmed/10465785
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