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Indian Hedgehog produced by postnatal chondrocytes is essential for maintaining a growth plate and trabecular bone

Indian hedgehog (Ihh) is essential for chondrocyte and osteoblast proliferation/differentiation during prenatal endochondral bone formation. The early lethality of various Ihh-ablated mutant mice, however, prevented further analysis of its role in postnatal bone growth and development. In this study...

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Autori principali: Maeda, Yukiko, Nakamura, Eiichiro, Nguyen, Minh-Thanh, Suva, Larry J., Swain, Frances L., Razzaque, Mohammed S., Mackem, Susan, Lanske, Beate
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851055/
https://ncbi.nlm.nih.gov/pubmed/17409191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608449104
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