Nef-mediated enhancement of cellular activation and human immunodeficiency virus type 1 replication in primary T cells is dependent on association with p21-activated kinase 2

BACKGROUND: The HIV-1 accessory protein Nef is an important determinant of lentiviral pathogenicity that contributes to disease progression by enhancing viral replication and other poorly understood mechanisms. Nef mediates diverse functions including downmodulation of cell surface CD4 and MHC Class...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Olivieri, Kevin C, Mukerji, Joya, Gabuzda, Dana
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2011
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169461/
https://ncbi.nlm.nih.gov/pubmed/21819585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-8-64
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