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Evidence for Adaptive Evolution at the Divergence Between Lymphoid and Brain HIV-1 nef Genes
Human immunodeficiency virus type 1 (HIV) infection of the central nervous system frequently causes HIV-associated neurocognitive disorders (HAND). The role of HIV Nef and other accessory proteins in HAND pathogenesis is unclear. To determine whether HIV nef undergoes adaptive selection in brain, we...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Mary Ann Liebert, Inc.
2010
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2933169/ https://ncbi.nlm.nih.gov/pubmed/20377428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2009.0257 |
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