p21-Activated Kinase 1 Plays a Critical Role in Cellular Activation by Nef

The activation of Nef-associated kinase (NAK) by Nef from human and simian immunodeficiency viruses is critical for efficient viral replication and pathogenesis. This induction occurs via the guanine nucleotide exchange factor Vav and the small GTPases Rac1 and Cdc42. In this study, we identified NA...

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Hauptverfasser: Fackler, Oliver T., Lu, Xiaobin, Frost, Jeffrey A., Geyer, Matthias, Jiang, Bing, Luo, Wen, Abo, Arie, Alberts, Arthur S., Peterlin, B. Matija
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
Schlagworte:
Cell Growth and Development
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC85477/
https://ncbi.nlm.nih.gov/pubmed/10713183
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