Human Immunodeficiency Virus Type 1 Nef Activates p21-Activated Kinase via Recruitment into Lipid Rafts

The Nef protein of human immunodeficiency virus type 1 is an important factor in AIDS pathogenesis. In addition to downregulating CD4 and major histocompatibility complex class I molecules from the cell surface, as well as increasing virion infectivity, Nef triggers activation of the T-cell receptor...

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Detalhes bibliográficos
Main Authors: Krautkrämer, Ellen, Giese, Simone I., Gasteier, Judith E., Muranyi, Walter, Fackler, Oliver T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC374280/
https://ncbi.nlm.nih.gov/pubmed/15047825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.8.4085-4097.2004
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