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Nef Associates with p21-Activated Kinase 2 in a p21-GTPase-Dependent Dynamic Activation Complex within Lipid Rafts

We have previously reported that Nef specifically interacts with a small but highly active subpopulation of p21-activated kinase 2 (PAK2). Here we show that this is due to a transient association of Nef with a PAK2 activation complex within a detergent-insoluble membrane compartment containing the l...

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Detalhes bibliográficos
Main Authors: Pulkkinen, Kati, Renkema, G. Herma, Kirchhoff, Frank, Saksela, Kalle
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC524974/
https://ncbi.nlm.nih.gov/pubmed/15542629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.23.12773-12780.2004
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