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Mechanisms of increased risk of tumorigenesis in Atm and Brca1 double heterozygosity
BACKGROUND: Both epidemiological and experimental studies suggest that heterozygosity for a single gene is linked with tumorigenesis and heterozygosity for two genes increases the risk of tumor incidence. Our previous work has demonstrated that Atm/Brca1 double heterozygosity leads to higher cell tr...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3169458/ https://ncbi.nlm.nih.gov/pubmed/21849032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-6-96 |
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