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Structure of trifunctional THI20 from yeast

In a recently characterized thiamin-salvage pathway, thiamin-degradation products are hydrolyzed by thiaminase II, yielding 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP). This compound is an intermediate in thiamin biosynthesis that, once phosphorylated by an HMP kinase, can be used to synthesize...

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Detalhes bibliográficos
Main Authors: French, Jarrod B., Begley, Tadhg P., Ealick, Steven E.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169313/
https://ncbi.nlm.nih.gov/pubmed/21904031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444911024814
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