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HMP Binding Protein ThiY and HMP-P Synthase THI5 are Structural Homologues,

The ATP-binding cassette transporter system ThiXYZ transports N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine (FAMP), a thiamin salvage pathway intermediate, into cells. FAMP is then converted to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP) and recycled into the thiamin biosynthetic pathway. T...

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Detalhes bibliográficos
Main Authors: Bale, Shridhar, Rajashankar, Kanagalaghatta R., Perry, Kay, Begley, Tadhg P., Ealick, Steven E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957805/
https://ncbi.nlm.nih.gov/pubmed/20873853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101209t
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