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The structural basis of RNA-catalyzed RNA polymerization
Early life presumably required polymerase ribozymes capable of replicating RNA. Known polymerase ribozymes best approximating such replicases use as their catalytic engine an RNA-ligase ribozyme originally selected from random RNA sequences. Here, we report 3.15 Å crystal structures of this ligase t...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3169305/ https://ncbi.nlm.nih.gov/pubmed/21857665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2107 |
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