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Novel RNA polymerization reaction catalyzed by a group I ribozyme.

We have converted a bacterial tRNA precursor containing a 205 nt self-splicing group I intron into a RNA enzyme that catalyzes polymerization of an external RNA substrate. The reaction involves transesterification steps analogous to both the forward and reverse exon ligation steps of group I splicin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chowrira, B M, Berzal-Herranz, A, Burke, J M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1993
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC413635/
https://ncbi.nlm.nih.gov/pubmed/7504625
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