Novel RNA polymerization reaction catalyzed by a group I ribozyme.

We have converted a bacterial tRNA precursor containing a 205 nt self-splicing group I intron into a RNA enzyme that catalyzes polymerization of an external RNA substrate. The reaction involves transesterification steps analogous to both the forward and reverse exon ligation steps of group I splicin...

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Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Chowrira, B M, Berzal-Herranz, A, Burke, J M
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413635/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7504625/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb06033.x
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