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Novel RNA polymerization reaction catalyzed by a group I ribozyme.
We have converted a bacterial tRNA precursor containing a 205 nt self-splicing group I intron into a RNA enzyme that catalyzes polymerization of an external RNA substrate. The reaction involves transesterification steps analogous to both the forward and reverse exon ligation steps of group I splicin...
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| Publicado no: | EMBO J |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413635/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7504625/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb06033.x |
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