Loading...
κ chain monoallelic demethylation and the establishment of allelic exclusion
Allelic exclusion in κ light-chain synthesis is thought to result from a feedback mechanism by which the expression of a functional κ light chain on the surface of the B cell leads to an intracellular signal that down-regulates the V(D)J recombinase, thus precluding rearrangement of the other allele...
Na minha lista:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
1998
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC316908/ https://ncbi.nlm.nih.gov/pubmed/9637682 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|