κ chain monoallelic demethylation and the establishment of allelic exclusion

Allelic exclusion in κ light-chain synthesis is thought to result from a feedback mechanism by which the expression of a functional κ light chain on the surface of the B cell leads to an intracellular signal that down-regulates the V(D)J recombinase, thus precluding rearrangement of the other allele...

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Bibliografiske detaljer

Udgivet i:	Genes Dev
Principais autores:	Mostoslavsky, Raul, Singh, Nandita, Kirillov, Andrei, Pelanda, Roberta, Cedar, Howard, Chess, Andrew, Bergman, Yehudit
Format:	Artigo
Sprog:	Inglês
Udgivet:	Cold Spring Harbor Laboratory Press 1998
Fag:	Research Paper
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316908/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9637682/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.12.1801
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