A cell cycle-dependent protein serves as a template-specific translation initiation factor

Cap-independent translation initiation on picornavirus mRNAs is mediated by an internal ribosomal entry site (IRES) in the 5′ untranslated region (5′ UTR) and requires both eukaryotic initiation factors (eIFs) and IRES-specific cellular trans-acting factors (ITAFs). We show here that the requirement...

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Main Authors: Pilipenko, Evgeny V., Pestova, Tatyana V., Kolupaeva, Victoria G., Khitrina, Elena V., Poperechnaya, Angela N., Agol, Vadim I., Hellen, Christopher U.T.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2000
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC316860/
https://ncbi.nlm.nih.gov/pubmed/10950867
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