Nuclear hormone receptor antagonism with AP-1 by inhibition of the JNK pathway

The activity of c-Jun, the major component of the transcription factor AP-1, is potentiated by amino-terminal phosphorylation on serines 63 and 73 (Ser-63/73). This phosphorylation is mediated by the Jun amino-terminal kinase (JNK) and required to recruit the transcriptional coactivator CREB-binding...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Caelles, Carme, González-Sancho, José M., Muñoz, Alberto
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 1997
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC316827/
https://ncbi.nlm.nih.gov/pubmed/9407028
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