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Glucocorticoid receptor–JNK interaction mediates inhibition of the JNK pathway by glucocorticoids

Inhibition of the c-Jun N-terminal kinase (JNK) pathway by glucocorticoids (GCs) results in AP-1 repression. GC antagonism of AP-1 relies mainly on the transrepression function of the GC receptor (GR) and mediates essential physiological and pharmacological actions. Here we show that GCs induce the...

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Bibliographic Details
Main Authors: Bruna, Alejandra, Nicolàs, Marta, Muñoz, Alberto, Kyriakis, John M., Caelles, Carme
Format: Artigo
Language:Inglês
Published: Oxford University Press 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC275446/
https://ncbi.nlm.nih.gov/pubmed/14609950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg590
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