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Mechanism of corepressor binding and release from nuclear hormone receptors

The association of transcription corepressors SMRT and N-CoR with retinoid and thyroid receptors results in suppression of basal transcriptional activity. A key event in nuclear receptor signaling is the hormone-dependent release of corepressor and the recruitment of coactivator. Biochemical and str...

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Detalhes bibliográficos
Main Authors: Nagy, Laszlo, Kao, Hung-Ying, Love, James D., Li, Chuan, Banayo, Ester, Gooch, John T., Krishna, V., Chatterjee, K., Evans, Ronald M., Schwabe, John W.R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC317208/
https://ncbi.nlm.nih.gov/pubmed/10617570
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