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The structure of the ultraspiracle ligand-binding domain reveals a nuclear receptor locked in an inactive conformation

Ultraspiracle (USP) is the invertebrate homologue of the mammalian retinoid X receptor (RXR). RXR plays a uniquely important role in differentiation, development, and homeostasis through its ability to serve as a heterodimeric partner to many other nuclear receptors. RXR is able to influence the act...

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Detalhes bibliográficos
Main Authors: Clayton, Gina M., Peak-Chew, Sew Y., Evans, Ronald M., Schwabe, John W. R.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC29294/
https://ncbi.nlm.nih.gov/pubmed/11171988
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