The structure of the ultraspiracle ligand-binding domain reveals a nuclear receptor locked in an inactive conformation

Ultraspiracle (USP) is the invertebrate homologue of the mammalian retinoid X receptor (RXR). RXR plays a uniquely important role in differentiation, development, and homeostasis through its ability to serve as a heterodimeric partner to many other nuclear receptors. RXR is able to influence the act...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Clayton, Gina M., Peak-Chew, Sew Y., Evans, Ronald M., Schwabe, John W. R.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2001
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC29294/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11171988/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.041611298
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