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The DAF-3 Smad protein antagonizes TGF-β-related receptor signaling in the Caenorhabditis elegans dauer pathway

Signals from TGF-β superfamily receptors are transduced to the nucleus by Smad proteins, which transcriptionally activate target genes. In Caenorhabditis elegans, defects in a TGF-β-related pathway cause a reversible developmental arrest and metabolic shift at the dauer larval stage. Null mutations...

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Detalhes bibliográficos
Main Authors: Patterson, Garth I., Koweek, Allison, Wong, Arthur, Liu, Yanxia, Ruvkun, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC316611/
https://ncbi.nlm.nih.gov/pubmed/9334330
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