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Nuclear hormone receptor antagonism with AP-1 by inhibition of the JNK pathway
The activity of c-Jun, the major component of the transcription factor AP-1, is potentiated by amino-terminal phosphorylation on serines 63 and 73 (Ser-63/73). This phosphorylation is mediated by the Jun amino-terminal kinase (JNK) and required to recruit the transcriptional coactivator CREB-binding...
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| Publié dans: | Genes Dev |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
1997
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316827/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9407028/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.11.24.3351 |
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