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osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification
Osteoprotegerin (OPG) is a secreted protein that inhibits osteoclast formation. In this study the physiological role of OPG is investigated by generating OPG-deficient mice. Adolescent and adult OPG(−/−) mice exhibit a decrease in total bone density characterized by severe trabecular and cortical bo...
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| Autori principali: | , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
1998
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC316769/ https://ncbi.nlm.nih.gov/pubmed/9573043 |
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