The Use of Somatic Hypermutation for the Affinity Maturation of Therapeutic Antibodies

le Bowers, Peter M., Boyle, William J., Damoiseaux, Robert
Foilsithe in Methods Mol Biol (2018)

Role of RANK ligand in mediating increased bone resorption in early postmenopausal women

le Eghbali-Fatourechi, Guitty, Khosla, Sundeep, Sanyal, Arunik, Boyle, William J., Lacey, David L., Riggs, B. Lawrence
Foilsithe 2003

Generating tumor-selective conditionally active biologic anti-CTLA4 antibodies via protein-associated chemical switches

le Chang, Hwai Wen, Frey, Gerhard, Liu, Haizhen, Xing, Charles, Steinman, Lawrence, Boyle, William J., Short, Jay M.
Foilsithe in Proc Natl Acad Sci U S A (2021)

osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification

le Bucay, Nathan, Sarosi, Ildiko, Dunstan, Colin R., Morony, Sean, Tarpley, John, Capparelli, Casey, Scully, Sheila, Tan, Hong Lin, Xu, Weilong, Lacey, David L., Boyle, William J., Simonet, W. Scott
Foilsithe 1998

Osteoprotegerin Reverses Osteoporosis by Inhibiting Endosteal Osteoclasts and Prevents Vascular Calcification by Blocking a Process Resembling Osteoclastogenesis

le Min, Hosung, Morony, Sean, Sarosi, Ildiko, Dunstan, Colin R., Capparelli, Casey, Scully, Sheila, Van, Gwyneth, Kaufman, Steve, Kostenuik, Paul J., Lacey, David L., Boyle, William J., Simonet, W. Scott
Foilsithe 2000

The Ligand for Osteoprotegerin (OPGL) Directly Activates Mature Osteoclasts

le Burgess, Teresa L., Qian, Yi-xin, Kaufman, Stephen, Ring, Brian D., Van, Gwyneth, Capparelli, Charles, Kelley, Michael, Hsu, Hailing, Boyle, William J., Dunstan, Colin R., Hu, Sylvia, Lacey, David L.
Foilsithe 1999

Osteoprotegerin Ligand Modulates Murine Osteoclast Survival in Vitro and in Vivo

le Lacey, David L., Tan, Hong Lin, Lu, John, Kaufman, Steven, Van, Gwyneth, Qiu, Wanrang, Rattan, Alana, Scully, Sheila, Fletcher, Frederick, Juan, Todd, Kelley, Michael, Burgess, Teresa L., Boyle, William J., Polverino, Anthony J.
Foilsithe 2000

Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice

le Khare, Sanjay D., Sarosi, Ildiko, Xia, Xing-Zhong, McCabe, Susan, Miner, Kent, Solovyev, Irina, Hawkins, Nessa, Kelley, Michael, Chang, David, Van, Gwyneth, Ross, Larry, Delaney, John, Wang, Ling, Lacey, David, Boyle, William J., Hsu, Hailing
Foilsithe 2000

Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand

le Hsu, Hailing, Lacey, David L., Dunstan, Colin R., Solovyev, Irina, Colombero, Anne, Timms, Emma, Tan, Hong-Lin, Elliott, Gary, Kelley, Michael J., Sarosi, Ildiko, Wang, Ling, Xia, Xing-Zhong, Elliott, Robin, Chiu, Laura, Black, Tabitha, Scully, Sheila, Capparelli, Casey, Morony, Sean, Shimamoto, Grant, Bass, Michael B., Boyle, William J.
Foilsithe 1999

Taci Is a Traf-Interacting Receptor for Tall-1, a Tumor Necrosis Factor Family Member Involved in B Cell Regulation

le Xia, Xing-Zhong, Treanor, James, Senaldi, Giorgio, Khare, Sanjay D., Boone, Tom, Kelley, Michael, Theill, Lars E., Colombero, Anne, Solovyev, Irina, Lee, Frances, McCabe, Susan, Elliott, Robin, Miner, Kent, Hawkins, Nessa, Guo, Jane, Stolina, Marina, Yu, Gang, Wang, Judy, Delaney, John, Meng, Shi-Yuan, Boyle, William J., Hsu, Hailing
Foilsithe 2000

RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism

le Li, Ji, Sarosi, Ildiko, Yan, Xiao-Qiang, Morony, Sean, Capparelli, Casey, Tan, Hong-Lin, McCabe, Susan, Elliott, Robin, Scully, Sheila, Van, Gwyneth, Kaufman, Stephen, Juan, Shao-Chieh, Sun, Yu, Tarpley, John, Martin, Laura, Christensen, Kathleen, McCabe, James, Kostenuik, Paul, Hsu, Hailing, Fletcher, Frederick, Dunstan, Colin R., Lacey, David L., Boyle, William J.
Foilsithe 2000

Coupling mammalian cell surface display with somatic hypermutation for the discovery and maturation of human antibodies

le Bowers, Peter M., Horlick, Robert A., Neben, Tamlyn Y., Toobian, Rachelle M., Tomlinson, Geoffrey L., Dalton, Jennifer L., Jones, Heather A., Chen, Andy, Altobell, Laurence, Zhang, Xue, Macomber, John L., Krapf, Irina P., Wu, Betty F., McConnell, Audrey, Chau, Betty, Holland, Trevin, Berkebile, Ashley D., Neben, Steven S., Boyle, William J., King, David J.
Foilsithe 2011

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

le Lomaga, Mark A., Yeh, Wen-Chen, Sarosi, Ildiko, Duncan, Gordon S., Furlonger, Caren, Ho, Alexandra, Morony, Sean, Capparelli, Casey, Van, Gwyneth, Kaufman, Stephen, van der Heiden, Annette, Itie, Annick, Wakeham, Andrew, Khoo, Wilson, Sasaki, Takehiko, Cao, Zhaodan, Penninger, Josef M., Paige, Christopher J., Lacey, David L., Dunstan, Colin R., Boyle, William J., Goeddel, David V., Mak, Tak W.
Foilsithe 1999