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Sub-Picogram Per Milliliter Determination of the Tobacco-Specific Carcinogen Metabolite 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in Human Urine Using Liquid Chromatography - Tandem Mass Spectrometry

Exposure to secondhand tobacco smoke (SHS) has been linked to increased risk for a number of diseases, including lung cancer. The tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) is of particular interest due to its potency and its specificity in producing lung tumor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jacob, Peyton, Havel, Christopher, Lee, Do-Hoon, Yu, Lisa, Eisner, Mark D., Benowitz, Neal L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167662/
https://ncbi.nlm.nih.gov/pubmed/18841944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac8009005
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