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A new liquid chromatography/mass spectrometry method for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in urine

4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) is a carcinogenic nitrosamine produced upon curing tobacco. It is present in tobacco smoke and undergoes metabolism to 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in the lungs. NNAL undergoes further uridine diphosphate glucuronosyltransf...

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Detalhes bibliográficos
Main Authors: Bhat, Showket H., Gelhaus, Stacy L., Mesaros, Clementina, Vachani, Anil, Blair, Ian A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348551/
https://ncbi.nlm.nih.gov/pubmed/21154658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rcm.4824
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