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The ClpXP and ClpAP proteases degrade proteins with carboxy-terminal peptide tails added by the SsrA-tagging system

Interruption of translation in Escherichia coli can lead to the addition of an 11-residue carboxy-terminal peptide tail to the nascent chain. This modification is mediated by SsrA RNA (also called 10Sa RNA and tmRNA) and marks the tagged polypeptide for proteolysis. Degradation in vivo of λ represso...

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Hlavní autoři: Gottesman, Susan, Roche, Eric, Zhou, YanNing, Sauer, Robert T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC316764/
https://ncbi.nlm.nih.gov/pubmed/9573050
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