Base pair opening kinetics study of the aegPNA:DNA hydrid duplex containing a site-specific GNA-like chiral PNA monomer

Peptide nucleic acids (PNA) are one of the most widely used synthetic DNA mimics where the four bases are attached to a N-(2-aminoethyl)glycine (aeg) backbone instead of the negative-charged phosphate backbone in DNA. We have developed a chimeric PNA (chiPNA), in which a chiral GNA-like γ(3)T monome...

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Hlavní autoři: Seo, Yeo-Jin, Lim, Jisoo, Lee, Eun-Hae, Ok, Taedong, Yoon, Juyoung, Lee, Joon-Hwa, Lee, Hee-Seung
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
Synthetic Biology and Chemistry
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167616/
https://ncbi.nlm.nih.gov/pubmed/21586589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr360
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