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Unique Properties of Purine/Pyrimidine Asymmetric PNA·DNA Duplexes: Differential Stabilization of PNA·DNA Duplexes by Purines in the PNA Strand

PNA·DNA duplexes are significantly stabilized by purine nucleobases in the PNA strand. To elucidate and understand the effect of switching the backbone in a nucleic acid duplex, we now report a thermodynamics study along with a solution conformations study of two purine/pyrimidine strand asymmetric...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sen, Anjana, Nielsen, Peter E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Biophysical Society 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367284/
https://ncbi.nlm.nih.gov/pubmed/16326919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.073213
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