Chiral introduction of positive charges to PNA for double-duplex invasion to versatile sequences

Invasion of two PNA strands to double-stranded DNA is one of the most promising methods to recognize a predetermined site in double-stranded DNA (PNA = peptide nucleic acid). In order to facilitate this ‘double-duplex invasion’, a new type of PNA was prepared by using chiral PNA monomers in which a...

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Main Authors: Ishizuka, Takumi, Yoshida, Junya, Yamamoto, Yoji, Sumaoka, Jun, Tedeschi, Tullia, Corradini, Roberto, Sforza, Stefano, Komiyama, Makoto
格式: Artigo
語言:Inglês
出版: Oxford University Press 2008
主題:
Chemistry
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275137/
https://ncbi.nlm.nih.gov/pubmed/18203747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm1154
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