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A pyrenyl-PNA probe for DNA and RNA recognition: Fluorescence and UV absorption studies

The design and the synthesis of a PNA oligomer containing a pyrenyl residue in the backbone were performed. PNA sequence was chosen complementary to a “G rich” target sequence involved in G-quadruplex formation. The pyrenyl unit replaced a nucleobase in the middle of the PNA through covalent linkage...

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Detalhes bibliográficos
Main Authors: Tedeschi, Tullia, Tonelli, Alessandro, Sforza, Stefano, Corradini, Roberto, Marchelli, Rosangela
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116571/
https://ncbi.nlm.nih.gov/pubmed/21686243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/adna.1.2.13899
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