PNA bearing 5-azidomethyluracil: A novel approach for solid and solution phase modification

Fmoc- and Boc-protected modified monomers bearing 5-azidomethyluracil nucleobase were synthesized. Four different solid-phase synthetic strategies were tested in order to evaluate the application of this series of monomers for the solid-phase synthesis of modified PNA. The azide was used as masked a...

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Bibliographic Details
Main Authors: Manicardi, Alex, Accetta, Alessandro, Tedeschi, Tullia, Sforza, Stefano, Marchelli, Rosangela, Corradini, Roberto
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429531/
https://ncbi.nlm.nih.gov/pubmed/22772040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/adna.20158
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