Endogenously induced DNA double strand breaks arise in heterochromatic DNA regions and require ataxia telangiectasia mutated and Artemis for their repair

Ataxia telangiectasia (ATM) mutated and Artemis, the proteins defective in ataxia telangiectasia and a class of Radiosensitive-Severe Combined Immunodeficiency (RS-SCID), respectively, function in the repair of DNA double strand breaks (DSBs), which arise in heterochromatic DNA (HC-DSBs) following e...

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Xehetasun bibliografikoak
Egile Nagusiak: Woodbine, Lisa, Brunton, H., Goodarzi, A. A., Shibata, A., Jeggo, P. A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2011
Gaiak:
Genome Integrity, Repair and Replication
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167608/
https://ncbi.nlm.nih.gov/pubmed/21596788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr331
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