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Comparative analysis of RNA-Seq alignment algorithms and the RNA-Seq unified mapper (RUM)
Motivation: A critical task in high-throughput sequencing is aligning millions of short reads to a reference genome. Alignment is especially complicated for RNA sequencing (RNA-Seq) because of RNA splicing. A number of RNA-Seq algorithms are available, and claim to align reads with high accuracy and...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2011
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3167048/ https://ncbi.nlm.nih.gov/pubmed/21775302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr427 |
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