IVT-seq reveals extreme bias in RNA sequencing

BACKGROUND: RNA-seq is a powerful technique for identifying and quantifying transcription and splicing events, both known and novel. However, given its recent development and the proliferation of library construction methods, understanding the bias it introduces is incomplete but critical to realizi...

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Detalhes bibliográficos
Main Authors: Lahens, Nicholas F, Kavakli, Ibrahim Halil, Zhang, Ray, Hayer, Katharina, Black, Michael B, Dueck, Hannah, Pizarro, Angel, Kim, Junhyong, Irizarry, Rafael, Thomas, Russell S, Grant, Gregory R, Hogenesch, John B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197826/
https://ncbi.nlm.nih.gov/pubmed/24981968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2014-15-6-r86
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