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Accounting for GC-content bias reduces systematic errors and batch effects in ChIP-seq data
The main application of ChIP-seq technology is the detection of genomic regions that bind to a protein of interest. A large part of functional genomics’ public catalogs is based on ChIP-seq data. These catalogs rely on peak calling algorithms that infer protein-binding sites by detecting genomic reg...
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| Pubblicato in: | Genome Res |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5668949/ https://ncbi.nlm.nih.gov/pubmed/29025895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.220673.117 |
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