Widespread Misinterpretable ChIP-seq Bias in Yeast

Chromatin immunoprecipitation followed by sequencing (ChIP-seq) is widely used to detect genome-wide interactions between a protein of interest and DNA in vivo. Loci showing strong enrichment over adjacent background regions are typically considered to be sites of binding. Insufficient attention has...

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Bibliographic Details
Main Authors: Park, Daechan, Lee, Yaelim, Bhupindersingh, Gurvani, Iyer, Vishwanath R.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857294/
https://ncbi.nlm.nih.gov/pubmed/24349523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083506
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