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Widespread Misinterpretable ChIP-seq Bias in Yeast
Chromatin immunoprecipitation followed by sequencing (ChIP-seq) is widely used to detect genome-wide interactions between a protein of interest and DNA in vivo. Loci showing strong enrichment over adjacent background regions are typically considered to be sites of binding. Insufficient attention has...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3857294/ https://ncbi.nlm.nih.gov/pubmed/24349523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083506 |
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