Llwytho...

Simulation-based comprehensive benchmarking of RNA-seq aligners

Alignment is the first step in most RNA-seq analysis pipelines, and the accuracy of downstream analyses depends heavily on it. Unlike most steps in the pipeline, alignment is particularly amenable to benchmarking with simulated data. We performed a comprehensive benchmarking of 14 common splice-awar...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Methods
Prif Awduron: Baruzzo, Giacomo, Hayer, Katharina E, Kim, Eun Ji, Di Camillo, Barbara, FitzGerald, Garret A, Grant, Gregory R
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792058/
https://ncbi.nlm.nih.gov/pubmed/27941783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4106
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