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In vitro generation of human cells with cancer stem cell properties

Cancer stem cells (CSCs) have been implicated in the maintenance and progression of several types of cancer. The origin and cellular properties of human CSCs are poorly characterized. Here we show that CSC-like cells can be generated in vitro by oncogenic reprogramming of human somatic cells during...

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Detalles Bibliográficos
Autores principales: Scaffidi, Paola, Misteli, Tom
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166977/
https://ncbi.nlm.nih.gov/pubmed/21857669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2308
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