Cells with stemness features are generated from in vitro transformed human fibroblasts

Cancer stem cells (CSCs) have been involved in the maintenance, progression and relapse of several tumors, but their origin is still elusive. Here, in vitro transformed human fibroblasts (cen3tel cells) and the tumorsphere assay were used to search for and possibly characterize CSCs in transformed s...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Bono, Bartolo, Ostano, Paola, Peritore, Martina, Gregnanin, Ilaria, Belgiovine, Cristina, Liguori, Manuela, Allavena, Paola, Chiorino, Giovanna, Chiodi, Ilaria, Mondello, Chiara
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138721/
https://ncbi.nlm.nih.gov/pubmed/30218041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32197-5
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