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Epithelial cell extrusion requires the sphingosine-1-phosphate receptor 2 pathway

To maintain an intact barrier, epithelia eliminate dying cells by extrusion. During extrusion, a cell destined for apoptosis signals its neighboring cells to form and contract a ring of actin and myosin, which squeezes the dying cell out of the epithelium. Here, we demonstrate that the signal produc...

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Detalles Bibliográficos
Main Authors: Gu, Yapeng, Forostyan, Tetyana, Sabbadini, Roger, Rosenblatt, Jody
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166871/
https://ncbi.nlm.nih.gov/pubmed/21555463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201010075
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