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Epithelial cell extrusion requires the sphingosine-1-phosphate receptor 2 pathway
To maintain an intact barrier, epithelia eliminate dying cells by extrusion. During extrusion, a cell destined for apoptosis signals its neighboring cells to form and contract a ring of actin and myosin, which squeezes the dying cell out of the epithelium. Here, we demonstrate that the signal produc...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3166871/ https://ncbi.nlm.nih.gov/pubmed/21555463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201010075 |
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