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Autophagy in oncogenic K-Ras promotes basal extrusion of epithelial cells by degrading S1P
BACKGROUND: To maintain a protective barrier, epithelia extrude cells destined to die by contracting a band of actin and myosin. Although extrusion can remove cells triggered to die by apoptotic stimuli, to maintain constant cell numbers, epithelia extrude live cells, which later die by anoikis. Bec...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3932369/ https://ncbi.nlm.nih.gov/pubmed/24361067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2013.11.029 |
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