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Autophagy in oncogenic K-Ras promotes basal extrusion of epithelial cells by degrading S1P

BACKGROUND: To maintain a protective barrier, epithelia extrude cells destined to die by contracting a band of actin and myosin. Although extrusion can remove cells triggered to die by apoptotic stimuli, to maintain constant cell numbers, epithelia extrude live cells, which later die by anoikis. Bec...

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Bibliografiske detaljer
Main Authors: Slattum, Gloria, Gu, Yapeng, Sabbadini, Roger, Rosenblatt, Jody
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932369/
https://ncbi.nlm.nih.gov/pubmed/24361067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2013.11.029
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