Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint
Chk1, an evolutionarily conserved protein kinase, has been implicated in cell cycle checkpoint control in lower eukaryotes. By gene disruption, we show that CHK1 deficiency results in a severe proliferation defect and death in embryonic stem (ES) cells, and peri-implantation embryonic lethality in m...
Tallennettuna:
| Julkaisussa: | Genes Dev |
|---|---|
| Päätekijät: | , , , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Cold Spring Harbor Laboratory Press
2000
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316686/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10859164/ |
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