Dendritic Cell Depletion Exacerbates Acetaminophen Hepatotoxicity

Acetaminophen (APAP) overdose is one of the most frequent causes of acute liver failure in the United States and is primarily mediated by toxic metabolites which accumulate in the liver upon depletion of glutathione stores. However, cells of the innate immune system, including NK cells, neutrophils,...

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Main Authors: Connolly, Michael K., Ayo, Diego, Malhotra, Ashim, Hackman, Michael, Bedrosian, Andrea S., Ibrahim, Junaid, Cieza-Rubio, Napoleon E., Nguyen, Andrew H., Henning, Justin R., Dorvil-Castro, Monica, Pachter, H. Leon, Miller, George
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166555/
https://ncbi.nlm.nih.gov/pubmed/21574173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24429
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